Is there any evidence that AGE/sRAGE is a universal biomarker/risk marker for diseases?
Sign Up to like & getrecommendations! Published in 2018 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-018-3400-2
Abstract: Advanced glycation end products (AGE) and its cell-bound receptor called receptor for AGE (RAGE) are implicated in the pathogenesis of numerous diseases. Soluble receptor for AGE (sRAGE) counteracts the adverse effects of AGE-RAGE interaction by… read more here.
Keywords: srage universal; age; age srage; srage ... See more keywords
Quantitative proteomics identifies the core proteome of exosomes with syntenin-1 as the highest abundant protein and a putative universal biomarker.
Sign Up to like & getrecommendations! Published in 2021 at "Nature cell biology"
DOI: 10.1038/s41556-021-00693-y
Abstract: Exosomes are extracellular vesicles derived from the endosomal compartment that are potentially involved in intercellular communication. Here, we found that frequently used biomarkers of exosomes are heterogeneous, and do not exhibit universal utility across different… read more here.
Keywords: proteome exosomes; putative universal; universal biomarker; abundant protein ... See more keywords