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Published in 2017 at "Immunity"
DOI: 10.1016/j.immuni.2017.09.007
Abstract: Development of a universal influenza vaccine is a research priority for the National Institute of Allergy and Infectious Diseases (NIAID) at the National Institutes of Health. To facilitate this goal, we convened a workshop in…
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Keywords:
influenza vaccine;
pathway universal;
universal influenza;
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Published in 2018 at "Virology"
DOI: 10.1016/j.virol.2018.08.021
Abstract: Influenza virus infections in humans and animals are major public health concerns. In the current study, a set of universal influenza enrichment probes was developed to increase the sensitivity of sequence-based virus detection and characterization…
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Keywords:
influenza virus;
enrichment probe;
virus;
universal influenza ... See more keywords
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Published in 2018 at "Expert Review of Vaccines"
DOI: 10.1080/14760584.2018.1541408
Abstract: ABSTRACT Introduction: The current seasonal influenza vaccine confers only limited protection due to waning antibodies or the antigenic shift and drift of major influenza surface antigens. A universal influenza vaccine which induces broad cross-protection against…
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Keywords:
vaccines viruses;
influenza vaccine;
influenza;
influenza vaccines ... See more keywords
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Published in 2019 at "PLoS ONE"
DOI: 10.1371/journal.pone.0215321
Abstract: Current approaches to influenza control rely on vaccines matched to viruses in circulation. Universal influenza vaccines would offer the advantage of providing broad protection against diverse strains of influenza virus. Candidate universal vaccines are developed…
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Keywords:
influenza vaccine;
vaccine;
candidate universal;
universal influenza ... See more keywords
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Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.01479
Abstract: Influenza viruses circulate worldwide causing annual epidemics that have a substantial impact on public health. This is despite vaccines being in use for over 70 years and currently being administered to around 500 million people each…
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Keywords:
influenza vaccine;
universal influenza;
realization implementation;
bench bedside ... See more keywords
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Published in 2020 at "Vaccines"
DOI: 10.3390/vaccines8030361
Abstract: Current influenza vaccines offer suboptimal protection and depend on annual reformulation and yearly administration. Vaccine technology has rapidly advanced during the last decade, facilitating development of next-generation influenza vaccines that can target a broader range…
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Keywords:
influenza vaccines;
universal influenza;
development;
development universal ... See more keywords
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Published in 2021 at "Vaccines"
DOI: 10.3390/vaccines9030257
Abstract: Influenza virus has significant viral diversity, both through antigenic drift and shift, which makes development of a vaccine challenging. Current influenza vaccines are updated yearly to include strains predicted to circulate in the upcoming influenza…
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Keywords:
vaccine strategies;
influenza vaccine;
strategies targeting;
universal influenza ... See more keywords