An unknown essential function of tRNA splicing endonuclease is linked to the integrated stress response and intron debranching.
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DOI: 10.1093/genetics/iyad044
Abstract: tRNA splicing endonuclease (TSEN) has a well-characterized role in tRNA splicing, but also other functions. For yeast TSEN, these other functions include degradation of a subset of mRNAs that encode mitochondrial proteins and an unknown… read more here.
Keywords: function; splicing endonuclease; intron debranching; essential function ... See more keywords