Unlocking the therapeutic potential of unexplored phytocompounds as hepatoprotective agents through integration of network pharmacology and in-silico analysis
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-92868-y
Abstract: Liver diseases account for over two million deaths annually, amounting to 4% of mortality worldwide, underscoring the need for development of novel preventive and therapeutic strategies. The growing interest in natural hepatoprotective agents highlights the… read more here.
Keywords: hepatoprotective agents; analysis; network pharmacology; pharmacology ... See more keywords
Unlocking the therapeutic potential of exosomes for ischemic stroke.
Sign Up to like & getrecommendations! Published in 2025 at "Biomaterials science"
DOI: 10.1039/d5bm01007a
Abstract: Ischemic stroke, a leading cause of global mortality and disability, faces therapeutic limitations due to the narrow time window and restricted efficacy of current interventions such as thrombolysis and thrombectomy. Recent advancements highlight exosomes-nanoscale extracellular… read more here.
Keywords: ischemic stroke; potential exosomes; therapeutic potential; exosomes ischemic ... See more keywords
Abstract A015: Unlocking therapeutic potential of rigosertib as a selective therapy for ovarian cancer
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Research"
DOI: 10.1158/1538-7445.genfunc25-a015
Abstract: Ovarian cancer has a devastating impact. In 2024 it is estimated that there will be 19,680 new ovarian cancer diagnoses and 12,740 fatalities in the United States. Despite advancements in treatment options, 80% of ovarian… read more here.
Keywords: cancer; potential rigosertib; therapeutic potential; unlocking therapeutic ... See more keywords
Unlocking the therapeutic potential and personalized therapy of testosterone: a comprehensive review
Sign Up to like & getrecommendations! Published in 2024 at "Drug Metabolism and Personalized Therapy"
DOI: 10.1515/dmpt-2024-0035
Abstract: Abstract Introduction Testosterone, the primary male sex hormone, orchestrates various physiological processes including sex differentiation, development of male characteristics, sperm production, and fertility. Its synthesis primarily occurs in Leydig cells within the testes, with smaller… read more here.
Keywords: review; therapeutic potential; personalized therapy; unlocking therapeutic ... See more keywords
Unlocking the Therapeutic Applicability of LNP-mRNA: Chemistry, Formulation, and Clinical Strategies
Sign Up to like & getrecommendations! Published in 2024 at "Research"
DOI: 10.34133/research.0370
Abstract: Messenger RNA (mRNA) has emerged as an innovative therapeutic modality, offering promising avenues for the prevention and treatment of a variety of diseases. The tremendous success of mRNA vaccines in effectively combatting coronavirus disease 2019… read more here.
Keywords: therapeutic applicability; chemistry; lnp mrna; unlocking therapeutic ... See more keywords