Circulating unmethylated insulin DNA as a potential non-invasive biomarker of beta cell death in type 1 Diabetes: a review and future prospect
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Epigenetics"
DOI: 10.1186/s13148-017-0343-5
Abstract: BackgroundThe early detection of type 1 diabetes (T1D) largely depends on a reliable approach to monitor β cell loss. An effective way to evaluate the decline of β cell mass would allow early preventative intervention… read more here.
Keywords: insulin; dna potential; type diabetes; unmethylated insulin ... See more keywords
Quantification of Unmethylated Insulin DNA Using Methylation Sensitive Restriction Enzyme Digital Polymerase Chain Reaction
Sign Up to like & getrecommendations! Published in 2022 at "Transplant International"
DOI: 10.3389/ti.2022.10167
Abstract: Assessment of specific β-cell death can be used to determine the quality and viability of pancreatic islets prior to transplantation and hence predict the suitability of the pancreas for isolation. Recently, several groups have demonstrated… read more here.
Keywords: ins dna; dna using; methylation sensitive; using methylation ... See more keywords