Antidepressant‐like effect of flaxseed in rats exposed to chronic unpredictable stress
Sign Up to like & getrecommendations! Published in 2020 at "Brain and Behavior"
DOI: 10.1002/brb3.1626
Abstract: Depression is a serious mental illness. However, a significant proportion of patients with depression fail to achieve remission with antidepressant therapies. This study was conducted to explore the antidepressant‐like effect of flaxseed oil and flour… read more here.
Keywords: unpredictable stress; chronic unpredictable; like effect; effect flaxseed ... See more keywords
Reduced growth capacity of preimplantation mouse embryos in chronic unpredictable stress model
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23439
Abstract: Psychological stress can affect female reproduction by deteriorating oocyte quality, but the molecular mechanism is unclear. In this study, we used the chronic unpredictable stress model to study the effect of psychological stress on mouse… read more here.
Keywords: unpredictable stress; chronic unpredictable; stress; stress model ... See more keywords
Rapid and sustained antidepressant effects of resolvin D1 and D2 in a chronic unpredictable stress model
Sign Up to like & getrecommendations! Published in 2017 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2017.06.010
Abstract: Resolvin D1 (RvD1) and D2 (RvD2) are lipid mediators that are derived from docosahexaenoic acid. We recently demonstrated that intracerebroventricular (i.c.v.) infusions of RvD1 or RvD2 attenuate lipopolysaccharide-induced depression-like behaviors via mammalian target of rapamycin… read more here.
Keywords: rapid sustained; unpredictable stress; chronic unpredictable; rvd1 rvd2 ... See more keywords
Rutin alleviates chronic unpredictable stress-induced behavioral alterations and hippocampal damage in mice
Sign Up to like & getrecommendations! Published in 2017 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2017.04.058
Abstract: Chronic stress results in neurological complications like depression, cognitive dysfunction, and anxiety disorders. In our previous study, we observed that Urtica dioica leaf extract attenuated chronic stress-induced complications. Further, we observed that Urtica dioica contained… read more here.
Keywords: unpredictable stress; chronic unpredictable; stress induced; stress ... See more keywords
5-HT2A receptor deficiency alters the metabolic and transcriptional, but not the behavioral, consequences of chronic unpredictable stress
Sign Up to like & getrecommendations! Published in 2017 at "Neurobiology of Stress"
DOI: 10.1016/j.ynstr.2017.06.001
Abstract: Chronic stress enhances risk for psychiatric disorders, and in animal models is known to evoke depression-like behavior accompanied by perturbed neurohormonal, metabolic, neuroarchitectural and transcriptional changes. Serotonergic neurotransmission, including serotonin2A (5-HT2A) receptors, have been implicated… read more here.
Keywords: ht2a; unpredictable stress; chronic unpredictable; ht2a receptor ... See more keywords
Behavioural characterisation of chronic unpredictable stress based on ethologically relevant paradigms in rats
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-53624-1
Abstract: The chronic unpredictable stress (CUS) paradigm is extensively used in preclinical research. However, CUS exhibits translational inconsistencies, some of them resulting from the use of adult rodents, despite the evidence that vulnerability for many psychiatric… read more here.
Keywords: cus; unpredictable stress; ethologically relevant; chronic unpredictable ... See more keywords
Subfield‐specific effects of chronic mild unpredictable stress on hippocampal astrocytes
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Neuroscience"
DOI: 10.1111/ejn.15234
Abstract: Major depressive disorder (MDD) is a debilitating neuropsychiatric illness affecting over 20% of the population worldwide. Despite its prevalence, our understanding of its pathophysiology is severely limited, thus hampering the development of novel therapeutic strategies.… read more here.
Keywords: mild unpredictable; unpredictable stress; stress; chronic mild ... See more keywords
Anxiolytic Effect of Carvedilol in Chronic Unpredictable Stress Model
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/6906722
Abstract: Anxiety disorders are the most prevalent psychiatric disorders being also a comorbid state of other diseases. We aimed to evaluate the anxiolytic-like effects of carvedilol (CVD), a drug used to treat high blood pressure and… read more here.
Keywords: unpredictable stress; effect; chronic unpredictable; anxiolytic effect ... See more keywords
Effect of Bromelain on Chronic Unpredictable Stress-induced Behavioral, Biochemical, and Monoamine Changes in Wistar Albino Rat Model of Depression.
Sign Up to like & getrecommendations! Published in 2023 at "Protein and peptide letters"
DOI: 10.2174/0929866530666230419093531
Abstract: BACKGROUND Bromelain is a complex mixture of protease enzyme extract from the fruit or stem of the pineapple plant and it has a history of folk medicine use. It is known to have a wide… read more here.
Keywords: unpredictable stress; bromelain; chronic unpredictable; group ... See more keywords
High-Fat Diet and Short-Term Unpredictable Stress Increase Long-Chain Ceramides Without Enhancing Behavioral Despair
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.859760
Abstract: Clinical and preclinical studies suggest that increases in long-chain ceramides in blood may contribute to the development of depressive-like behavior. However, which factors contribute to these increases and whether the increases are sufficient to induce… read more here.
Keywords: long chain; chain ceramides; high fat; unpredictable stress ... See more keywords
The Effects of Rosiglitazone on Task Specific Anxiety-Like Behavior and Novelty Seeking in a Model of Chronic Adolescent Unpredictable Stress
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Behavioral Neuroscience"
DOI: 10.3389/fnbeh.2022.830310
Abstract: Adolescence is characterized as a period of increased social behavior, risk taking, and novelty seeking, partly due to ongoing maturation in critical brain areas and the hypothalamic-pituitary-adrenal (HPA) negative-feedback system. During this period there is… read more here.
Keywords: novelty seeking; stress; risk taking; adolescent unpredictable ... See more keywords