An Organometallic Gold(III) Reagent for 18F Labeling of Unprotected Peptides and Sugars in Aqueous Media.
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DOI: 10.1021/acs.orglett.2c01965
Abstract: The 18F labeling of unprotected peptides and sugars with a Au(III)-[18F]fluoroaryl complex is reported. The chemoselective method generates 18F-labeled S-aryl bioconjugates in an aqueous environment in 15 min with high radiochemical yields and displays excellent… read more here.
Keywords: 18f labeling; iii; peptides sugars; labeling unprotected ... See more keywords
Rapid phenolic O-glycosylation of small molecules and complex unprotected peptides in aqueous solvent
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DOI: 10.1038/s41557-018-0041-8
Abstract: AbstractGlycosylated natural products and synthetic glycopeptides represent a significant and growing source of biochemical probes and therapeutic agents. However, methods that enable the aqueous glycosylation of endogenous amino acid functionality in peptides without the use… read more here.
Keywords: phenolic glycosylation; complex unprotected; small molecules; glycosylation ... See more keywords
Ring closing metathesis of unprotected peptides.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical communications"
DOI: 10.1039/c7cc04100d
Abstract: An efficient and expedient route to the synthesis of dicarba peptides from protecting group-free sequences is reported using Ru-alkylidene catalysed olefin metathesis. A range of cyclic peptides was prepared from linear peptides containing two Z-crotyl… read more here.
Keywords: unprotected peptides; metathesis unprotected; closing metathesis; metathesis ... See more keywords