Unraveling the Signaling Balance of Activation and Exhaustion of CAR T Cells.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer cell"
DOI: 10.1016/j.ccell.2020.01.006
Abstract: CAR T cells with different costimulation domains have proven clinical efficacy in leukemia and lymphoma but have different kinetics of activation, antigen sensitivity, and susceptibility to exhaustion. Two recent studies identified that these functions are shaped… read more here.
Keywords: unraveling signaling; car; activation; car cells ... See more keywords