The prognostic role of soluble TGF‐beta and its dynamics in unresectable pancreatic cancer treated with chemotherapy
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Medicine"
DOI: 10.1002/cam4.2677
Abstract: Transforming growth factor‐beta (TGF‐β) is a multifunctional regulatory factor. Here we measured serum soluble TGF‐β (sTGF‐β) levels and evaluated its dynamics and prognostic capabilities during chemotherapy in unresectable pancreatic cancer patients. read more here.
Keywords: unresectable pancreatic; pancreatic cancer; beta; cancer ... See more keywords
Role of Conversion Surgery for Unresectable Pancreatic Cancer After Long-Term Chemotherapy
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DOI: 10.1007/s00268-020-05503-4
Abstract: Background Unresectable pancreatic cancer (UR-PC) has a poor prognosis. Although conversion surgery has been considered a promising strategy for improving prognosis in UR-PC, the clinical benefit offered to patients with UR-PC remains controversial. This study… read more here.
Keywords: long term; surgery; unresectable pancreatic; conversion surgery ... See more keywords
Phase 1 study of Gemcitabine/Nab-paclitaxel/S-1 in patients with unresectable pancreatic cancer (GeNeS1S trial)
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-020-04174-1
Abstract: Purpose We conducted a phase 1 study to determine the maximum tolerated dose and the recommended dose of gemcitabine/nab-paclitaxel/S-1 combination chemotherapy in patients with unresectable pancreatic cancer. Methods We enrolled patients aged 20 years or older… read more here.
Keywords: nab paclitaxel; unresectable pancreatic; gemcitabine; gemcitabine nab ... See more keywords
Predictors of analgesic efficacy of neurolytic celiac plexus block in patients with unresectable pancreatic cancer: the importance of timing
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DOI: 10.1007/s00520-018-4043-2
Abstract: BackgroundNeurolytic celiac plexus block (NCPB) is a safe and effective method for reducing abdominal cancer pain. However, the analgesic efficacy of NCPB is not always guaranteed. The aim of this retrospective study was to identify… read more here.
Keywords: good analgesia; unresectable pancreatic; analgesic efficacy; cancer ... See more keywords
Simulation study of dosimetric effect in proton beam therapy using concomitant boost technique for unresectable pancreatic cancers
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DOI: 10.1007/s11604-018-0743-2
Abstract: PurposeThe purpose of this study is to investigate the dose distribution of proton beam therapy (PBT) using a concomitant boost technique for unresectable pancreatic cancers.Materials and methodsThis simulation study involved 36 patients with unresectable pancreatic… read more here.
Keywords: unresectable pancreatic; boost technique; study; concomitant boost ... See more keywords
Acute pancreatitis after percutaneous insertion of metallic biliary stents in patients with unresectable pancreatic cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical radiology"
DOI: 10.1016/j.crad.2019.07.014
Abstract: AIM To investigate the incidence and clinical characteristics of acute pancreatitis following percutaneous insertion of metallic biliary stents in patients with unresectable pancreatic cancer. The clinical efficacy of metallic stent insertion was also evaluated. MATERIALS… read more here.
Keywords: acute pancreatitis; unresectable pancreatic; insertion; biliary stents ... See more keywords
Stereotactic body radiation vs. intensity-modulated radiation for unresectable pancreatic cancer
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DOI: 10.1080/0284186x.2017.1342863
Abstract: Abstract Background: Stereotactic body radiation therapy (SBRT) is an emerging treatment option for unresectable pancreatic cancer, and is postulated to be more effective and less toxic than conventionally fractionated intensity modulated radiation therapy (IMRT). Material… read more here.
Keywords: unresectable pancreatic; pancreatic cancer; toxicity; body radiation ... See more keywords
Management of elderly patients with unresectable pancreatic cancer.
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DOI: 10.1093/jjco/hyac101
Abstract: Systemic chemotherapy plays important role in pancreatic cancer not only for palliative treatment of unresectable disease, but also for neoadjuvant and adjuvant treatment of resectable disease. Most clinical trials of systemic chemotherapy have been conducted… read more here.
Keywords: unresectable pancreatic; elderly patients; pancreatic cancer; management elderly ... See more keywords
Sarcopenia: Prognostic Value for Unresectable Pancreatic Ductal Adenocarcinoma Patients Treated With Gemcitabine Plus Nab-Paclitaxel.
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DOI: 10.1097/mpa.0000000000001985
Abstract: OBJECTIVE The aim of the study was to clarify the association of skeletal muscle mass and the prognosis of unresectable pancreatic ductal adenocarcinoma (PDAC) treated with gemcitabine plus nab-paclitaxel (GnP). METHODS We included 124 unresectable… read more here.
Keywords: sarcopenia; unresectable pancreatic; gemcitabine plus; treated gemcitabine ... See more keywords
Response to the Comment on "Prognostic Factors of Survival After Neoadjuvant Treatment and Resection for Initially Unresectable Pancreatic Cancer".
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DOI: 10.1097/sla.0000000000003651
Abstract: To the Editor: We read with great interest the article entitled ‘‘Prognostic Factors of Survival After Neoadjuvant Treatment and Resection for Initially Unresectable Pancreatic Cancer.’’ We would like to congratulate the authors for their insights… read more here.
Keywords: status; treatment; unresectable pancreatic; resection ... See more keywords
Evaluation of palliative treatments in unresectable pancreatic cancer
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DOI: 10.1111/ans.16669
Abstract: Pancreatic ductal adenocarcinoma (PDAC) presents as unresectable disease in 80% of patients. Limited Australian data exists regarding management and outcome of palliative management for PDAC. This study aims to: (i) identify patients with PDAC being… read more here.
Keywords: treatments unresectable; unresectable pancreatic; pancreatic cancer; palliative treatments ... See more keywords