OrienX010, an oncolytic virus, in patients with unresectable stage IIIC–IV melanoma: a phase Ib study
Sign Up to like & getrecommendations! Published in 2022 at "Journal for Immunotherapy of Cancer"
DOI: 10.1136/jitc-2021-004307
Abstract: Background Melanoma in people of Asian descent presents primarily in non-sun-exposed areas, such as acral and mucosal melanoma. Compared with the predominant sun-exposed area melanomas in Caucasians, acral and mucosal melanomas do not respond as… read more here.
Keywords: unresectable stage; patients unresectable; melanoma; cohort ... See more keywords
Neoadjuvant chemotherapy by bronchial arterial infusion in patients with unresectable stage III squamous cell lung cancer
Sign Up to like & getrecommendations! Published in 2017 at "Therapeutic Advances in Respiratory Disease"
DOI: 10.1177/1753465817717169
Abstract: Background: We investigated the effects of neoadjuvant chemotherapy administered via bronchial arterial infusion (BAI) on unresectable stage III lung squamous cell carcinoma (SCC). Methods: This was a single-arm retrospective study of chemotherapy with gemcitabine plus… read more here.
Keywords: chemotherapy; stage iii; unresectable stage; neoadjuvant chemotherapy ... See more keywords
Current challenges of unresectable stage III NSCLC: are we ready to break the glass ceiling of the PACIFIC trial?
Sign Up to like & getrecommendations! Published in 2022 at "Therapeutic Advances in Medical Oncology"
DOI: 10.1177/17588359221113268
Abstract: Consolidation anti-programmed death-ligand 1 has become a new standard of care in unresectable stage III non-small cell lung cancer (NSCLC) following chemo-radiotherapy (CTRT), based on the results of two phase III trials. Advances remain however… read more here.
Keywords: iii nsclc; unresectable stage; stage iii; current challenges ... See more keywords
Phase II study of ipilimumab (IPI) in children and adolescents with unresectable stage III or IV malignant melanoma (MEL).
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.e21006
Abstract: e21006Background: IPI (anti-CTLA4) is approved for treatment of advanced MEL in adults, and more information on efficacy and safety of IPI in younger patients (pts) is needed. Methods: Pts from study CA184-178 (NCT01696045) age 12… read more here.
Keywords: mel; iii malignant; stage iii; unresectable stage ... See more keywords
Consolidation nivolumab/ipilimumab versus nivolumab following concurrent chemoradiation in patients with unresectable stage III NSCLC: A planned interim safety analysis from the BTCRC LUN 16-081 trial.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.9010
Abstract: 9010Background: Consolidation PD-1/PD-L1 inhibition after chemoradiation (CRT) for unresectable stage III NSCLC improves overall survival. In stage IV NSCLC, the combination of nivolumab/ipilimumab... read more here.
Keywords: consolidation; stage iii; unresectable stage; iii nsclc ... See more keywords
ASO Author Reflections: Prognostic Impact of Primary Tumor Sidedness for Unresectable Stage IV Colorectal Cancer
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Surgical Oncology"
DOI: 10.1245/s10434-019-07666-4
Abstract: Many biological differences exist between the right-side colon and the left-side colon, including differing embryologic origins, distinct site-associated microbiota, and differential gene expression and methylation. Recent studies have reported a prognostic value for primary tumor… read more here.
Keywords: tumor sidedness; unresectable stage; colorectal cancer; primary tumor ... See more keywords
Cost-effectiveness analysis of durvalumab as a maintenance treatment for patients with locally advanced, unresectable, stage Ⅲ nsclc in china
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0270118
Abstract: Objective The aim of this study was to evaluate the cost-effectiveness of durvalumab compared with Best supportive care (BSC) after chemoradiotherapy in patients with stage III non-small cell lung cancer from healthcare system perspective in… read more here.
Keywords: rmb; cost; unresectable stage; china ... See more keywords
Durvalumab after concurrent chemoradiotherapy in a patient with chemotherapy-resistant unresectable stage III non-small cell lung cancer: a case report.
Sign Up to like & getrecommendations! Published in 2020 at "Annals of palliative medicine"
DOI: 10.21037/apm-20-1118
Abstract: Durvalumab as consolidative immunotherapy following concurrent chemoradiotherapy (cCRT) is the standard treatment for patients with unresectable stage III non-small cell lung cancer (NSCLC). Here, we describe a case of unresectable stage III NSCLC who was… read more here.
Keywords: chemotherapy; concurrent chemoradiotherapy; stage iii; unresectable stage ... See more keywords
Concurrent sintilimab with sequential chemoradiotherapy for unresectable, stage III non-small cell lung cancer: a retrospective study
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1129989
Abstract: Background Concurrent programmed death 1 (PD-1) or programmed death ligand 1 (PD-L1) inhibitors with sequential chemoradiotherapy (SCRT) have been reported in only a limited number of studies involving patients with unresectable stage III non-small-cell lung… read more here.
Keywords: retrospective study; stage iii; concurrent sintilimab; unresectable stage ... See more keywords
The role of upfront primary tumor resection in asymptomatic patients with unresectable stage IV colorectal cancer: A systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Surgery"
DOI: 10.3389/fsurg.2022.1047373
Abstract: Background Controversy exists over the role of upfront primary tumor resection (PTR) in asymptomatic patients with unresectable stage IV colorectal cancer (CRC). The purpose of this study was to evaluate the effect of upfront PTR… read more here.
Keywords: review; ptr; patients unresectable; systematic review ... See more keywords
Surgery for Unresectable Stage IIIC and IV Melanoma in the Era of New Systemic Therapy
Sign Up to like & getrecommendations! Published in 2020 at "Cancers"
DOI: 10.3390/cancers12051176
Abstract: Opportunities for surgical treatment in metastatic melanoma patients have re-emerged due to the development of novel systemic therapeutics over the past decade. The aim of this study is to present data on outcomes of surgery… read more here.
Keywords: melanoma; surgery; unresectable stage; systemic therapy ... See more keywords