Rhodium-Catalyzed Highly Enantio- and Diastereoselective Alkenylation of β,γ-Unsaturated Butenolides via Dynamic Kinetic Resolution.
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DOI: 10.1021/acs.orglett.2c03551
Abstract: A rhodium-catalyzed highly enantio- and diastereoselective alkenylation of β,γ-unsaturated butenolides is reported. The use of a chiral diene ligand, (S,S)-Ph-bod, enables the facile synthesis of chiral butyrolactones in high yields with extremely high enantioselectivities (>99%… read more here.
Keywords: alkenylation; enantio diastereoselective; rhodium catalyzed; unsaturated butenolides ... See more keywords