Dearomatization/Deiodination of o-Iodophenolic Compounds with α,β-Unsaturated Imines for Accessing Benzofuran Derivatives.
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DOI: 10.1021/acs.orglett.1c04065
Abstract: A dearomatization/deiodination/rearomatization strategy for the [3 + 2] cyclization of o-iodophenolic substrates with α,β-unsaturated imines to construct various dihydrobenzofuran-related skeletons has been established. Tolerance to different functional groups has been tested. Mechanistic studies revealed that… read more here.
Keywords: deiodination iodophenolic; deiodination; compounds unsaturated; dearomatization deiodination ... See more keywords
Synthesis of Cyclopenta[b]indoles via Sc(III)-Catalyzed Annulation of Vinyl Diazoacetates with Indole-Derived Unsaturated Imines.
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DOI: 10.1021/acs.orglett.3c00192
Abstract: A Lewis acid Sc(OTf)3-catalyzed annulation reaction of vinyl diazoacetates with in situ formed α,β-unsaturated imines for the preparation of indole-fused tricyclic rings has been reported. This strategy involves a sequential addition/rebound addition process of vinyl… read more here.
Keywords: catalyzed annulation; annulation; vinyl diazoacetates; synthesis cyclopenta ... See more keywords
Palladium-catalyzed asymmetric [3 + 2] cycloaddition of vinyl aziridines and α,β-unsaturated imines generated in situ from aryl sulfonyl indoles
Sign Up to like & getrecommendations! Published in 2021 at "Organic chemistry frontiers"
DOI: 10.1039/d1qo00408e
Abstract: The first palladium-catalyzed asymmetric formal [3 + 2] cycloaddition of vinyl aziridines and in situ generated unsaturated imines has been established. read more here.
Keywords: catalyzed asymmetric; palladium catalyzed; vinyl aziridines; unsaturated imines ... See more keywords