Cinchonidine-Catalyzed Synthesis of Oxazabicyclo[4.2.1]nonanones from N-Aryl-α,β-unsaturated Nitrones and 1-Ethynylnaphthalen-2-ols.
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DOI: 10.1021/acs.orglett.2c01049
Abstract: A variety of oxazabicyclo[4.2.1]nonanone derivatives were prepared in good yields through a cinchonidine-catalyzed cascade reaction of N-aryl-α,β-unsaturated nitrones and 1-ethynylnaphthalen-2-ols. Mechanistic studies show that the reaction undergoes a [4 + 3] cycloaddition of nitrones to… read more here.
Keywords: aryl unsaturated; ethynylnaphthalen ols; unsaturated nitrones; oxazabicyclo nonanones ... See more keywords
Synthesis of 1,2,4-Oxadiazolines through Deoxygenative Cyclization of N-Vinyl-α,β-Unsaturated Nitrones with in Situ Generated Nitrile Oxides from Hydroxamoyl Chlorides.
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DOI: 10.1021/acs.orglett.2c04121
Abstract: A variety of 1,2,4-oxadiazoline derivatives were synthesized in moderate to good yields through a deoxygenative cyclization cascade reaction of N-vinyl-α,β-unsaturated nitrones and hydroxamoyl chlorides. Mechanistic studies revealed that the reaction underwent double additions of nitrile… read more here.
Keywords: deoxygenative cyclization; hydroxamoyl chlorides; unsaturated nitrones; vinyl unsaturated ... See more keywords