Palladacycle promoted asymmetric hydrophosphination of α,β-unsaturated sulfonyl fluorides
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Organometallic Chemistry"
DOI: 10.1016/j.jorganchem.2019.120912
Abstract: Abstract The first example of an enantioselective hydrophosphination reaction of ethenesulfonyl fluoride derivatives catalyzed by a phosphapalladacycle afforded chiral sulfonyl fluoride-derived phosphines in quantitative yields and enantioselectivities of up to 93% ee. Investigations revealed the… read more here.
Keywords: unsaturated sulfonyl; hydrophosphination; palladacycle promoted; asymmetric hydrophosphination ... See more keywords
Olefination with Sulfonyl Halides and Esters: Synthesis of Unsaturated Sulfonyl Fluorides
Sign Up to like & getrecommendations! Published in 2022 at "Organic Letters"
DOI: 10.1021/acs.orglett.2c01604
Abstract: Methanedisulfonyl fluoride, CH2(SO2F)2, transforms aromatic aldehydes into β-arylethenesulfonyl fluorides, useful substrates for the SuFEx “click”-type transformations. The reaction mimics mechanism of the Horner–Wadsworth–Emmons olefination, which runs via addition of the carbanion, followed by cyclization–fragmentation of… read more here.
Keywords: synthesis unsaturated; olefination sulfonyl; unsaturated sulfonyl; halides esters ... See more keywords
Palladium-Catalyzed Asymmetric 1,4-Addition of Diarylphosphines to α,β-Unsaturated Sulfonyl Fluorides
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DOI: 10.1055/a-2067-7071
Abstract: A Pd-catalyzed asymmetric phosphination of α, β-unsaturated sulfonyl fluorides was developed, and a series of tertiary phosphorus compounds were obtained in excellent yields and enantioselectivities (up to 99% ee). The chiral adduct can be further… read more here.
Keywords: unsaturated sulfonyl; palladium catalyzed; asymmetric addition; catalyzed asymmetric ... See more keywords