New 3‐unsubstituted isoxazolones as potent human neutrophil elastase inhibitors: Synthesis and molecular dynamic simulation
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DOI: 10.1002/ddr.21625
Abstract: Human neutrophil elastase (HNE) is a proteolytic enzyme belonging to the serine protease family and is involved in a variety of pathologies. Thus, compounds able to inhibit HNE represent promising therapeutics for the treatment of… read more here.
Keywords: unsubstituted isoxazolones; human neutrophil; neutrophil elastase; new unsubstituted ... See more keywords