Three-Component Reactions of Aromatic Amines, 1,3-Dicarbonyl Compounds and α-Bromoacetaldehyde Acetal to Access N-Aryl/HetAryl-4,5-Unsubstituted Pyrroles
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DOI: 10.3762/bxiv.2020.94.v1
Abstract: N-Aryl/HetAryl-4,5-unsubstituted pyrroles were synthesized from Ar/HetAr-amines, 1,3-dicarbonyl compounds and α-bromoacetaldehyde acetal by using aluminum(III) chloride as a Lewis acid catalyst through [1 + 2 + 2] annulation. This new versatile methodology provides a wide scope… read more here.
Keywords: aryl hetaryl; unsubstituted pyrroles; hetaryl unsubstituted; amines dicarbonyl ... See more keywords