Palladium-Catalyzed Regio- and Stereoselective Hydroaminocarbonylation of Unsymmetrical Internal Alkynes toward α,β-Unsaturated Amides.
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DOI: 10.1021/acs.orglett.2c01693
Abstract: α,β-Unsaturated amides play a vital role in natural products, pharmaceuticals, organic synthesis, and functional materials. Herein, we disclosed a regio- and stereoselective hydroaminocarbonylation of unsymmetrical internal alkynes via palladium catalysis to synthesize α,β-unsaturated amides. This… read more here.
Keywords: internal alkynes; hydroaminocarbonylation unsymmetrical; unsymmetrical internal; regio stereoselective ... See more keywords