Comprehensive lipidomics of mouse plasma using class-specific surrogate calibrants and SWATH acquisition for large-scale lipid quantification in untargeted analysis.
Sign Up to like & getrecommendations! Published in 2019 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2019.08.030
Abstract: Lipidomics has gained rising attention in recent years. Several strategies for lipidomic profiling have been developed, with targeted analysis of selected lipid species, typically utilized for lipid quantification by low-resolution triple quadrupole MS/MS, and untargeted… read more here.
Keywords: untargeted analysis; acquisition; surrogate calibrants; quantification ... See more keywords
Untargeted analysis of first trimester serum to reveal biomarkers of pregnancy complications: a case–control discovery phase study
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-82804-1
Abstract: Understanding of causal biology and predictive biomarkers are lacking for hypertensive disorders of pregnancy (HDP) and preterm birth (PTB). First-trimester serum specimens from 51 cases of HDP, including 18 cases of pre-eclampsia (PE) and 33… read more here.
Keywords: analysis; pregnancy complications; untargeted analysis; trimester serum ... See more keywords
Untargeted LC–MS/MS analysis reveals metabolomics feature of osteosarcoma stem cell response to methotrexate
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Cell International"
DOI: 10.1186/s12935-020-01356-y
Abstract: Background Cancer stem cell (CSC) is identified in osteosarcoma (OS) and considered resistant to chemotherapeutic agents. However, the mechanism of osteosarcoma stem cell (OSC) resistant to chemotherapy remains debatable and vague, and the metabolomics feature… read more here.
Keywords: metabolomics feature; untargeted analysis; response; stem cell ... See more keywords