Untargeted screening of phase I metabolism of combretastatin A4 by multi-tool analysis.
Sign Up to like & getrecommendations! Published in 2018 at "Talanta"
DOI: 10.1016/j.talanta.2018.01.051
Abstract: The aim of the current study was to apply different strategies for generation of metabolites of combretastatin A4 (CA4) and subsequent identification of the unknown products of phase I metabolism. CA4 is a potent anti-tubulin… read more here.
Keywords: screening phase; metabolism; multi tool; phase metabolism ... See more keywords
Cell-Based Metabolomics for Untargeted Screening and Prioritization of Vertebrate-Active Stressors in Streams Across the United States.
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DOI: 10.1021/acs.est.9b02736
Abstract: The U.S. Geological Survey and the U.S. Environmental Protection Agency have assessed contaminants in 38 streams across the U.S., using an extensive suite of target-chemical analysis methods along with a variety of biological effects tools.… read more here.
Keywords: streams across; cell based; screening prioritization; based metabolomics ... See more keywords
Untargeted Metabolomics Studies on Drug-Incubated Phragmites australis Profiles
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DOI: 10.3390/metabo11010002
Abstract: Plants produce a huge number of functionally and chemically different natural products that play an important role in linking the plant with the adjacent environment. Plants can also absorb and transform external organic compounds (xenobiotics).… read more here.
Keywords: phragmites australis; metabolomics studies; studies drug; drug ... See more keywords