Using Physical Organic Chemistry Knowledge to Predict Unusual Metabolites of Synthetic Phenolic Antioxidants by Cytochrome P450.
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DOI: 10.1021/acs.chemrestox.2c00021
Abstract: Biotransformation, especially by human CYP450 enzymes, plays a crucial role in regulating the toxicity of organic compounds in organisms, but is poorly understood for most emerging pollutants, as their numerous "unusual" biotransformation reactions cannot retrieve… read more here.
Keywords: organic chemistry; phenolic antioxidants; synthetic phenolic; unusual metabolites ... See more keywords