Ruthenium-Catalyzed Intermolecular [2 + 2] Cycloaddition of Unactivated Allenes and Alkynes with Unusual Regioselectivity
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DOI: 10.1021/jacs.5c11285
Abstract: Described here is an efficient protocol for intermolecular [2 + 2] cycloaddition of unactivated and unsymmetrical allenes and alkynes with unusual regioselectivity, counterintuitively favoring the most hindered isomer. CpRu(MeCN)3PF6 served as a uniquely effective catalyst,… read more here.
Keywords: regioselectivity; intermolecular cycloaddition; cycloaddition unactivated; unusual regioselectivity ... See more keywords