Genomic and Targeted Approaches Unveil the Cell Membrane as a Major Target of the Antifungal Cytotoxin Amantelide A
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DOI: 10.1002/cbic.202000685
Abstract: Amantelide A, a polyhydroxylated macrolide isolated from a marine cyanobacterium, displays broadâspectrum activity against mammalian cells, bacterial pathogens, and marine fungi. We conducted comprehensive mechanistic studies to identify the molecular targets and pathways affected by… read more here.
Keywords: approaches unveil; targeted approaches; unveil cell; cell ... See more keywords