The convergence of head-on DNA unwinding forks induces helicase oligomerization and activity transition
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DOI: 10.1073/pnas.2116462119
Abstract: Significance Bloom syndrome helicase (BLM) is a multifunctional helicase that primarily catalyzes the separation of two single strands of DNA. Here, using a single-molecule optical tweezers approach combined with confocal microscopy, we monitored both the… read more here.
Keywords: convergence head; unwinding forks; dna unwinding; head dna ... See more keywords