Articles with "unwrapped nucleosomes" as a keyword



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PHF1 Tudor and N-terminal domains synergistically target partially unwrapped nucleosomes to increase DNA accessibility

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Published in 2017 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkw1320

Abstract: Abstract The Tudor domain of human PHF1 recognizes trimethylated lysine 36 on histone H3 (H3K36me3). PHF1 relies on this interaction to regulate PRC2 methyltransferase activity, localize to DNA double strand breaks and mediate nucleosome accessibility.… read more here.

Keywords: unwrapped nucleosomes; dna; accessibility; dna accessibility ... See more keywords
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Specialization of the chromatin remodeler RSC to mobilize partially-unwrapped nucleosomes

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Published in 2020 at "eLife"

DOI: 10.7554/elife.58130

Abstract: SWI/SNF-family chromatin remodeling complexes, such as S. cerevisiae RSC, slide and eject nucleosomes to regulate transcription. Within nucleosomes, stiff DNA sequences confer spontaneous partial unwrapping, prompting whether and how SWI/SNF-family remodelers are specialized to remodel… read more here.

Keywords: unwrapped nucleosomes; remodel partially; partially unwrapped; specialization chromatin ... See more keywords