The growth of siRNA-based therapeutics: updated clinical studies.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2021.114432
Abstract: More than two decades after the natural gene-silencing mechanism of RNA interference was elucidated, small interfering RNA (siRNA)-based therapeutics have finally broken into the pharmaceutical market. With three agents already approved and many others in… read more here.
Keywords: clinical studies; sirna based; growth sirna; based therapeutics ... See more keywords
Reporting Items for Updated Clinical Guidelines: Checklist for the Reporting of Updated Guidelines (CheckUp)
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DOI: 10.1371/journal.pmed.1002207
Abstract: Background Scientific knowledge is in constant development. Consequently, regular review to assure the trustworthiness of clinical guidelines is required. However, there is still a lack of preferred reporting items of the updating process in updated… read more here.
Keywords: guideline; methodology; reporting updated; clinical guidelines ... See more keywords
Letter to the Editor: 'Updated clinical evidence and place in therapy of bempedoic acid (BA) for hypercholesterolemia: aNMCO position paper'.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cardiovascular Medicine"
DOI: 10.2459/jcm.0000000000001150
Abstract: To the Editor The recently published ‘Updated clinical evidence and place in therapy of bempedoic acid (BA) for hypercholesterolemia: aNMCO position paper’ by Colivicchi et al. reviewed the mechanism of action and the efficacy and… read more here.
Keywords: evidence place; hypercholesterolemia; updated clinical; clinical evidence ... See more keywords