An updated patent review of VEGFR-2 inhibitors (2017-present)
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DOI: 10.1080/13543776.2021.1935872
Abstract: ABSTRACT Introduction: Angiogenesis is a vital process for cellular functions in both physiological and pathophysiological conditions and is one of the hallmarks of cancer progression and metastasis. VEGF/VEGFR-2 signaling pathway has been recognized as the… read more here.
Keywords: patent review; review vegfr; updated patent; vegfr inhibitors ... See more keywords
An updated patent review on drugs for the treatment of tuberculosis (2018-present)
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DOI: 10.1080/13543776.2022.2012151
Abstract: ABSTRACT Introduction Tuberculosis (TB) caused by Mycobacterium tuberculosis (M.tb) has been a global challenge as 1.4 million deaths were reported in 2019, which included deaths attributed to HIV-TB co-infection. It is curable by the prescribed… read more here.
Keywords: review; drug; tuberculosis; 2018 present ... See more keywords
An updated patent review of glutaminase inhibitors (2019–2022)
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DOI: 10.1080/13543776.2023.2173573
Abstract: ABSTRACT Introduction Kidney-type glutaminase (GLS1), a key enzyme controlling the hydrolysis of glutamine to glutamate to resolve the ‘glutamine addiction’ of cancer cells, has been shown to play a central role in supporting cancer growth… read more here.
Keywords: gls1; gls1 inhibitors; updated patent; patent review ... See more keywords
An updated patent review of Nrf2 activators (2020-present)
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DOI: 10.1080/13543776.2023.2178299
Abstract: ABSTRACT Introduction The nuclear factor erythroid 2-related factor 2 (Nrf2) is a pivotal transcription factor that controls the expression of numerous cytoprotective genes and regulates cellular defense system against oxidative insults. Thus, activating the Nrf2… read more here.
Keywords: updated patent; patent review; nrf2 activators; activators 2020 ... See more keywords