An Updated Safety Review of the Relationship Between Atypical Antipsychotic Drugs, the QTc Interval and Torsades de Pointe As: Implications for Clinical Use
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DOI: 10.1080/14740338.2024.2392002
Abstract: ABSTRACT Introduction The rising prevalence of psychiatric disorders has resulted in a significant increase in the use of antipsychotic medications. These agents may prolong the corrected QT interval (QTc), running the risk of precipitating ventricular… read more here.
Keywords: review; use; updated safety; qtc interval ... See more keywords
Development and Psychometric Analysis of a Nurses' Attitudes and Skills Safety Scale: Initial Results
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DOI: 10.1097/ncq.0000000000000216
Abstract: Health care organizations have incorporated updated safety principles in the analysis of errors and in norms and standards. Yet no research exists that assesses bedside nurses' perceived skills or attitudes toward updated safety concepts. The… read more here.
Keywords: perceived skills; safety; skills attitudes; updated safety ... See more keywords
Abstract B016: Updated Safety, Efficacy and Biomarker Analysis from the Phase I Study of Givastomig, a Novel Claudin 18.2/4-1BB Bispecific Antibody, in Claudin 18.2 Positive Advanced Gastroesophageal Carcinoma (GEC)
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DOI: 10.1158/1535-7163.targ-25-b016
Abstract: Claudin 18.2 (CLDN18.2) is a validated target in GEC, but novel approaches are needed. Givastomig/ABL111 (giva) is a first-in-class, bispecific antibody targeting tumoral CLDN18.2 and 4-1BB on adjacent T cells, preferentially activating T cells in… read more here.
Keywords: cldn18; bispecific antibody; updated safety; gec ... See more keywords