Modulators of CFTR. Updates on clinical development and future directions.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2021.113195
Abstract: Cystic fibrosis (CF) is the most frequent life-limiting autosomal recessive disorder in the Caucasian population. It is due to mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene. Current symptomatic CF therapies, which treat… read more here.
Keywords: cftr updates; development future; clinical development; future directions ... See more keywords
Key updates in the clinical application of electroconvulsive therapy
Sign Up to like & getrecommendations! Published in 2017 at "International Review of Psychiatry"
DOI: 10.1080/09540261.2017.1309362
Abstract: Abstract ECT is the oldest and most effective therapy available for the treatment of severe major depression. It is highly effective in individuals with treatment resistance and when a rapid response is required. However, ECT… read more here.
Keywords: treatment; evidence; key updates; therapy ... See more keywords
Schistosome proteomics: updates and clinical implications
Sign Up to like & getrecommendations! Published in 2022 at "Expert Review of Proteomics"
DOI: 10.1080/14789450.2022.2142565
Abstract: ABSTRACT Introduction Schistosomes are long-lived blood dwelling helminth parasites using intricate mechanisms to invade, mature, and reproduce inside their vertebrate hosts, whilst simultaneously deploying immune evasion strategies. Their multi-tissue organization and solid body plan presents… read more here.
Keywords: updates clinical; clinical implications; schistosome proteomics; proteomics updates ... See more keywords
Recent Updates to Clinical Practice Guidelines for Diabetes Mellitus
Sign Up to like & getrecommendations! Published in 2022 at "Endocrinology and Metabolism"
DOI: 10.3803/enm.2022.105
Abstract: Guidelines for the management of patients with diabetes have become an important part of clinical practice that improve the quality of care and help establish evidence-based medicine in this field. With rapidly accumulating evidence on… read more here.
Keywords: guidelines diabetes; practice; practice guidelines; updates clinical ... See more keywords