RNA sequencing of synaptic and cytoplasmic Upf1-bound transcripts supports contribution of nonsense-mediated decay to epileptogenesis
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DOI: 10.1038/srep41517
Abstract: The nonsense mediated decay (NMD) pathway is a critical surveillance mechanism for identifying aberrant mRNA transcripts. It is unknown, however, whether the NMD system is affected by seizures in vivo and whether changes confer beneficial… read more here.
Keywords: mediated decay; status epilepticus; rna sequencing; nmd pathway ... See more keywords