Comparison of Survival Outcomes Among Human Papillomavirus–Negative cT1-2 N1-2b Patients With Oropharyngeal Squamous Cell Cancer Treated With Upfront Surgery vs Definitive Chemoradiation Therapy: An Observational Study
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Oncology"
DOI: 10.1001/jamaoncol.2016.5769
Abstract: Importance Human papillomavirus (HPV)-negative oropharyngeal squamous cell carcinoma (OPSCC) has shown resistance to conventional concurrent chemoradiation (CRT) therapy and carries a relatively poor prognosis in comparison with HPV-positive disease, with decreased locoregional control and overall… read more here.
Keywords: surgery; observational study; ct1; therapy ... See more keywords
Axillary lymph node dissection in node-positive breast cancer: are ten nodes adequate and when is enough, enough?
Sign Up to like & getrecommendations! Published in 2019 at "Breast Cancer Research and Treatment"
DOI: 10.1007/s10549-019-05500-9
Abstract: Purpose National guidelines define adequate axillary lymph node dissections as those yielding ≥ 10 lymph nodes (LNs). We aimed to identify the optimal LN yield among node-positive patients. Methods Using the National Cancer Data Base (2010–2015), we… read more here.
Keywords: lymph; breast cancer; node positive; upfront surgery ... See more keywords
Analysis of Carcinoma of the Esophagus Patients Between Upfront Surgery vs. Neoadjuvant Therapy Followed by Surgery
Sign Up to like & getrecommendations! Published in 2020 at "Indian Journal of Surgery"
DOI: 10.1007/s12262-020-02156-4
Abstract: In the management of carcinoma of the esophagus, neoadjuvant chemoradiation has shown to improve survival in many Western studies. It has still not become the standard of care in many centers due to perioperative morbidity/mortality… read more here.
Keywords: carcinoma esophagus; surgery; neoadjuvant therapy; upfront surgery ... See more keywords
Neoadjuvant therapy offers longer survival than upfront surgery for poorly differentiated and higher stage pancreatic cancer
Sign Up to like & getrecommendations! Published in 2018 at "Acta Oncologica"
DOI: 10.1080/0284186x.2017.1415458
Abstract: Abstract Background: Neoadjuvant therapy for pancreatic cancer remains controversial. Our aim was to assess differences in survival, disease recurrence and histopathological tumor characteristics between patients treated with neoadjuvant therapy followed by subsequent surgery and patients… read more here.
Keywords: patients treated; neoadjuvant therapy; therapy; treated neoadjuvant ... See more keywords
Survival outcome of upfront surgery for clinical single-station N2 non-small cell lung cancer.
Sign Up to like & getrecommendations! Published in 2023 at "Japanese journal of clinical oncology"
DOI: 10.1093/jjco/hyac209
Abstract: BACKGROUND Pathological N2 (pN2) non-small cell lung cancer (NSCLC) is diverse; its treatment depends on the clinical N (cN) status. We aimed to determine the efficacy of upfront surgery for cN2pN2 NSCLC. METHODS The study… read more here.
Keywords: non small; surgery; survival; upfront surgery ... See more keywords
Survival outcomes of neoadjuvant therapy followed by radical resection versus upfront surgery for stage I-III pancreatic ductal adenocarcinoma: a retrospective cohort study.
Sign Up to like & getrecommendations! Published in 2023 at "International journal of surgery"
DOI: 10.1097/js9.0000000000000425
Abstract: BACKGROUND Neoadjuvant therapy remains controversial in treating resectable pancreatic ductal adenocarcinoma (PDAC) patients. This study aims to assess the impact of neoadjuvant therapy on survival in patients with PDAC according to their clinical stage. METHODS… read more here.
Keywords: neoadjuvant therapy; surgery; stage iii; stage ... See more keywords
Estimating Recurrence after Upfront Surgery in Patients with Resectable Pancreatic Ductal Adenocarcinoma by Using Pancreatic CT: Development and Validation of a Risk Score.
Sign Up to like & getrecommendations! Published in 2020 at "Radiology"
DOI: 10.1148/radiol.2020200281
Abstract: Background No preoperative model is available for predicting postsurgical prognosis of patients with resectable pancreatic ductal adenocarcinoma (PDAC). Purpose To develop and validate a preoperative risk scoring system using clinical and CT variables to predict… read more here.
Keywords: risk; recurrence; patients resectable; risk score ... See more keywords
Endometrial Cancer: When Upfront Surgery Is Not an Option.
Sign Up to like & getrecommendations! Published in 2020 at "Oncology"
DOI: 10.1159/000510690
Abstract: Background and Summary: The management of endometrial cancer, in an ever-older population with considerable comorbidity, remains a challenge for gynecological and radiation oncologists. Key Message: The present paper reviews literature data on treatment options for… read more here.
Keywords: surgery option; cancer upfront; endometrial cancer; cancer ... See more keywords
Neoadjuvant Chemoradiotherapy Versus Upfront Surgery for Resectable and Borderline Resectable Pancreatic Cancer: Long-Term Results of the Dutch Randomized PREOPANC Trial
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.21.02233
Abstract: PURPOSE The benefit of neoadjuvant chemoradiotherapy in resectable and borderline resectable pancreatic cancer remains controversial. Initial results of the PREOPANC trial failed to demonstrate a statistically significant overall survival (OS) benefit. The long-term results are… read more here.
Keywords: chemoradiotherapy; resectable borderline; surgery; neoadjuvant chemoradiotherapy ... See more keywords
Accuracy of sentinel node mapping in patients with biopsy-proven metastatic axillary lymph nodes and upfront surgery: preliminary results of the Multimodal Targeted Axillary Surgery (MUTAS) trial
Sign Up to like & getrecommendations! Published in 2022 at "Gland Surgery"
DOI: 10.21037/gs-22-480
Abstract: Background Some studies suggested that the patients included in the Z0011 trial may represent patients with ultrasound-negative axillary nodes and axillary invasion diagnosed by sentinel node (SN) biopsy. Nevertheless, the National Comprehensive Cancer Network (NCCN)… read more here.
Keywords: proven metastatic; mapping patients; axillary nodes; biopsy proven ... See more keywords
Upfront Surgery vs. Primary Chemoradiation in an Unselected, Bicentric Patient Cohort with Oropharyngeal Squamous Cell Carcinoma—A Matched-Pair Analysis
Sign Up to like & getrecommendations! Published in 2021 at "Cancers"
DOI: 10.3390/cancers13215265
Abstract: Simple Summary Oropharyngeal squamous cell carcinoma (OPSCC) is a common malignancy of the upper aerodigestive tract with rising incidence. While surgical and non-surgical approaches are applied in curative treatment, none of these has proven superior… read more here.
Keywords: treatment; matched pair; upfront surgery; primary chemoradiation ... See more keywords