Discovery and Comparison of Serum Biomarkers for Diabetes Mellitus and Metabolic Syndrome Based on UPLC-Q-TOF/MS.
Sign Up to like & getrecommendations! Published in 2020 at "Clinical biochemistry"
DOI: 10.1016/j.clinbiochem.2020.03.007
Abstract: INTRODUCTION Diabetes mellitus (DM) and metabolic syndrome (MetS) are systemic metabolic disorders, which have risk factors for diabetic cardiovascular and cerebral microvascular disease. It is very important to screen the metabolic biomarkers between DM and… read more here.
Keywords: based uplc; diabetes mellitus; metabolic syndrome; mellitus metabolic ... See more keywords
A UPLC-Q-TOF-MS-based metabolomics approach for the evaluation of fermented mare's milk to koumiss.
Sign Up to like & getrecommendations! Published in 2020 at "Food chemistry"
DOI: 10.1016/j.foodchem.2020.126619
Abstract: The fermentation of mare's milk into koumiss produces many beneficial functional compounds depending on the metabolism of the initial microbial flora. In this study, metabolites found in mare's milk and resulting koumiss were identified. Major… read more here.
Keywords: mare milk; tof based; uplc tof; milk koumiss ... See more keywords
Metabolic profiling of copper‐laden hepatolenticular degeneration model rats and the interventional effects of Gandou decoction using UPLC‐Q‐TOF/MS
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2018.10.041
Abstract: Graphical abstract Figure. No Caption available. HighlightsCopper‐laden rat model was established to study the therapeutic effect of Gandou decoction (GDD) on hepatolenticular degeneration (HLD).A UPLC‐Q‐TOF/MS‐based serum metabolomic approach was used to further provide a global… read more here.
Keywords: hepatolenticular degeneration; metabolism; hld; copper ... See more keywords
Systematic analysis of the metabolites of Angelicae Pubescentis Radix by UPLC-Q-TOF-MS combined with metabonomics approaches after oral administration to rats.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2020.113445
Abstract: Angelicae Pubescentis Radix (APR) is a typical Traditional Chinese Medicine (TCM) and has been widely used to treat rheumatism and headache diseases in China. This research aimed to illustrate the metabolites of APR in vivo… read more here.
Keywords: combined metabonomics; metabonomics approaches; angelicae pubescentis; pubescentis radix ... See more keywords
Metabolomics study on liver of db/db mice treated with curcumin using UPLC-Q-TOF-MS.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2022.114771
Abstract: A metabolomics method based on ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF-MS) was applied to study the metabolic changes of liver in db/db mice administered with curcumin. After one week of acclimating to feeding,… read more here.
Keywords: treatment group; uplc tof; treatment; liver mice ... See more keywords
Lipidomics Profiling of HepG2 Cells and Interference by Mycotoxins Based on UPLC-TOF-IMS.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c05543
Abstract: Discovering the fungus-infected or mycotoxin-contaminated biomarkers is significant for systems biology since the metabolites in biological samples have significant polarity differences in both stochastic gene expression and microenvironmental change. Here, we aim to establish a… read more here.
Keywords: uplc tof; tof ims; interference mycotoxins; lipidomics profiling ... See more keywords
Profile of Human Milk Phospholipids at Different Lactation Stages with UPLC/Q-TOF-MS: Characterization, Distribution, and Differences.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c07512
Abstract: Human milk phospholipids are important for the regular growth and development of infants. Ultra-high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC/Q-TOF-MS) was employed to qualitatively and quantitatively analyze 277 phospholipid molecular species in 112 human milk… read more here.
Keywords: uplc tof; human milk; profile human; milk phospholipids ... See more keywords
UPLC-Q-TOF/MS-Based Plasma and Urine Metabolomics Contribute to the Diagnosis of Sepsis.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.1c00777
Abstract: In this study, we aimed to identify potential metabolic biomarkers that can improve the diagnostic accuracy of sepsis. Sixty-six patients including 30 septic and 36 nonsepsis patients from an intensive care unit were recruited. The… read more here.
Keywords: sepsis; tof based; plasma urine; diagnosis ... See more keywords
UPLC/Q-TOF-MS-based Metabolomics Study of the Antiosteoporosis Effects of Vaccarin in Ovariectomized Mice
Sign Up to like & getrecommendations! Published in 2022 at "Planta Medica"
DOI: 10.1055/a-1942-5428
Abstract: Abstract Osteoporosis is a systemic and metabolic bone disease that usually occurs in postmenopausal women, which mainly manifests as bone loss and increased bone fragility that both facilitate fracture. However, few drugs for osteoporosis have… read more here.
Keywords: uplc tof; antiosteoporosis; effects vaccarin; tof based ... See more keywords
Characterization of alkaloids in radix Sophora tonkinensis by UPLC-Q-TOF-MS/MS and its application in the comparison of two different habitats.
Sign Up to like & getrecommendations! Published in 2020 at "Natural product research"
DOI: 10.1080/14786419.2020.1771712
Abstract: Sophora tonkinensis is widely used as traditional Chinese medicine for treating the swelling of the gums and tongue and mouth sores due to flame stomach fire. It is mainly origin from Guangxi, Sichuan provinces of… read more here.
Keywords: tonkinensis root; alkaloids tonkinensis; sophora tonkinensis; tonkinensis ... See more keywords
Systematic characterisation of the effective components of five Callicarpa species with UPLC-Q-TOF-MS and evaluation of their anti-hyperuricaemic activity
Sign Up to like & getrecommendations! Published in 2022 at "Natural Product Research"
DOI: 10.1080/14786419.2022.2102628
Abstract: Abstract Callicarpa kwangtungensis (C. Kw), C. macrophylla (C. Ma), C. nudiflora (C. Nu), C. formosana (C. Fo), and C. kochiana (C. Ko) were medicinal plant resource in China. In this study, the UPLC/Q-TOF-MS analysis was… read more here.
Keywords: uplc tof; callicarpa species; systematic characterisation; five callicarpa ... See more keywords