Protein Folding upon Binding Revealed by Molecular Dynamics Simulation
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DOI: 10.1016/j.bpj.2016.11.329
Abstract: Macromolecules frequently associate in living cells and tissues, where specific binding interactions based on dynamic conformation regulate molecular localization and activity. Despite the rapidly expanding experimental characterization of the structural proteome, the combinatorial explosion of… read more here.
Keywords: binding revealed; upon binding; folding upon; protein folding ... See more keywords
Allosteric couplings upon binding of RfaH to transcription elongation complexes
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac453
Abstract: Abstract In every domain of life, NusG-like proteins bind to the elongating RNA polymerase (RNAP) to support processive RNA synthesis and to couple transcription to ongoing cellular processes. Structures of factor-bound transcription elongation complexes (TECs)… read more here.
Keywords: nusg rfah; transcription; transcription elongation; elongation complexes ... See more keywords
Structural rearrangements in mRNA upon its binding to human 80S ribosomes revealed by EPR spectroscopy
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DOI: 10.1093/nar/gkx1136
Abstract: Abstract The model mRNA (MR), 11-mer RNA containing two nitroxide spin labels at the 5′- and 3′-terminal nucleotides and prone to form a stable homodimer (MR)2, was used for Electron Paramagnetic Resonance study of structural… read more here.
Keywords: rearrangements mrna; upon binding; structural rearrangements; binding human ... See more keywords