XAF1 prevents hyperproduction of type I interferon upon viral infection by targeting IRF7
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DOI: 10.15252/embr.202255387
Abstract: Interferon regulatory factor (IRF) 3 and IRF7 are master regulators of type I interferon (IFN‐I)‐dependent antiviral innate immunity. Upon viral infection, a positive feedback loop is formed, wherein IRF7 promotes further induction of IFN‐I in… read more here.
Keywords: viral infection; upon viral; interferon; xaf1 ... See more keywords