Articles with "upr signaling" as a keyword



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Combination of Salviae Miltiorrhizae Radix et Rhizoma and Carthami Flos improves cardiac function of diabetic cardiomyopathy mice by regulating the unfolded protein response signaling pathway

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Published in 2022 at "Phytotherapy Research"

DOI: 10.1002/ptr.7524

Abstract: Diabetic cardiomyopathy (DCM) is a unique clinical entity elicited by diabetes independent of other cardiovascular risk factors, of which the pathological mechanisms and treatment strategies remain largely undefined. This study aimed to clarify the role… read more here.

Keywords: function; signaling pathway; dcm mice; upr signaling ... See more keywords
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Unfolding the Interactions between Endoplasmic Reticulum Stress and Oxidative Stress

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Published in 2023 at "Antioxidants"

DOI: 10.3390/antiox12050981

Abstract: Oxidative stress is caused by an imbalance in cellular redox state due to the accumulation of reactive oxygen species (ROS). While homeostatic levels of ROS are important for cell physiology and signaling, excess ROS can… read more here.

Keywords: endoplasmic reticulum; stress; oxidative stress; unfolding interactions ... See more keywords