Intermedin alleviates pathological cardiac remodeling by upregulating klotho.
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DOI: 10.1016/j.phrs.2020.104926
Abstract: Cardiac remodeling is accompanied by cardiac hypertrophy, fibrosis, dysfunction, and eventually leading to heart failure. Intermedin (IMD), as a paracrine/autocrine peptide, has a protective effect in cardiovascular diseases. In this study, we elucidated the role… read more here.
Keywords: imd; upregulating klotho; cardiac remodeling; mice ... See more keywords