Articles with "upregulation harakiri" as a keyword



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Ruthenium Complex HB324 Induces Apoptosis via Mitochondrial Pathway with an Upregulation of Harakiri and Overcomes Cisplatin Resistance in Neuroblastoma Cells In Vitro

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Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24020952

Abstract: Ruthenium(II) complexes with N-heterocyclic carbene (NHC) ligands have recently attracted attention as novel chemotherapeutic agents. The complex HB324 was intensively studied as an apoptosis-inducing compound in resistant cell lines. HB324 induced apoptosis via mitochondrial pathways.… read more here.

Keywords: apoptosis via; complex hb324; upregulation harakiri; hb324 ... See more keywords