KRIT1 loss-mediated upregulation of NOX1 in stromal cells promotes paracrine pro-angiogenic responses.
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DOI: 10.1016/j.cellsig.2020.109527
Abstract: Cerebral cavernous malformation (CCM) is a cerebrovascular disorder of proven genetic origin characterized by abnormally dilated and leaky capillaries occurring mainly in the central nervous system, with a prevalence of 0.3-0.5% in the general population.… read more here.
Keywords: stromal cells; upregulation nox1; mediated upregulation; krit1 loss ... See more keywords