m6A-dependent upregulation of TRAF6 by METTL3 is associated with metastatic osteosarcoma
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DOI: 10.1016/j.jbo.2022.100411
Abstract: Highlights • METTL3 is highly expressed in osteosarcoma.• METTL3 downregulation inhibits metastases of osteosarcoma cells.• m6A regulates osteosarcoma cell activity.• METTL3 modifies TRAF6 activity via m6A.• TRAF6 inhibits the repressive effects of sh-METTL3 on osteosarcoma… read more here.
Keywords: upregulation traf6; mettl3; m6a dependent; osteosarcoma ... See more keywords