Does eIF3 promote reinitiation after translation of short upstream ORFs also in mammalian cells?
Sign Up to like & getrecommendations! Published in 2017 at "RNA Biology"
DOI: 10.1080/15476286.2017.1353863
Abstract: ABSTRACT Reinitiation after translation of short upstream ORFs (uORFs) represents one of the means of regulation of gene expression on the mRNA-specific level in response to changing environmental conditions. Over the years it has been… read more here.
Keywords: reinitiation translation; reinitiation; translation short; translation ... See more keywords
In vivo evidence that eIF3 stays bound to ribosomes elongating and terminating on short upstream ORFs to promote reinitiation
Sign Up to like & getrecommendations! Published in 2017 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkx049
Abstract: Abstract Translation reinitiation is a gene-specific translational control mechanism characterized by the ability of some short upstream ORFs to prevent recycling of the post-termination 40S subunit in order to resume scanning for reinitiation downstream. Its… read more here.
Keywords: reinitiation; vivo evidence; upstream orfs; short upstream ... See more keywords