Identification of key genes and upstream regulators in ischemic stroke
Sign Up to like & getrecommendations! Published in 2019 at "Brain and Behavior"
DOI: 10.1002/brb3.1319
Abstract: Ischemic stroke (IS) causes severe neurological impairments and physical disabilities and has a high economic burden. Our study aims to identify the key genes and upstream regulators in IS by integrated microarray analysis. read more here.
Keywords: regulators ischemic; ischemic stroke; identification key; genes upstream ... See more keywords
Upstream regulators of phosphoinositide 3‐kinase and their role in diseases
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DOI: 10.1002/jcp.28215
Abstract: Phosphoinositide 3‐kinase (PI3K), a crucial signaling molecule, is regulated by various upstream regulators. Traditionally, receptor tyrosine kinases and G protein‐coupled receptor are regarded as its principle upstream regulators; however, recent reports have indicated that spleen… read more here.
Keywords: kinase role; regulators phosphoinositide; upstream regulators; role diseases ... See more keywords
Meta-Analysis of Expression Profiling Data Indicates Need for Combinatorial Biomarkers in Pediatric Ulcerative Colitis
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Immunology Research"
DOI: 10.1155/2020/8279619
Abstract: Background Unbiased studies using different genome-wide methods have identified a great number of candidate biomarkers for diagnosis and treatment response in pediatric ulcerative colitis (UC). However, clinical translation has been proven difficult. Here, we hypothesized… read more here.
Keywords: pediatric ulcerative; upstream regulators; predicted upstream; expression ... See more keywords
Upstream Regulators of Fibroblast Growth Factor 23
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DOI: 10.3389/fendo.2021.588096
Abstract: Fibroblast growth factor 23 (FGF23) has been described as an important regulator of mineral homeostasis, but has lately also been linked to iron deficiency, inflammation, and erythropoiesis. FGF23 is essential for the maintenance of phosphate… read more here.
Keywords: growth factor; upstream regulators; fibroblast growth; regulators fibroblast ... See more keywords
Analysis of Upstream Regulators, Networks, and Pathways Associated With the Expression Patterns of Polycystic Ovary Syndrome Candidate Genes During Fetal Ovary Development
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.762177
Abstract: Polycystic Ovary Syndrome (PCOS) is a multifactorial syndrome with reproductive, endocrine, and metabolic symptoms, affecting about 10% women of reproductive age. Pathogenesis of the syndrome is poorly understood with genetic and fetal origins being the… read more here.
Keywords: candidate genes; development; polycystic ovary; upstream regulators ... See more keywords