Systemic lupus erythematosus variants modulate the function of an enhancer upstream of TNFAIP3
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DOI: 10.3389/fgene.2022.1011965
Abstract: TNFAIP3/A20 is a prominent autoimmune disease risk locus that is correlated with hypomorphic TNFAIP3 expression and exhibits complex chromatin architecture with over 30 predicted enhancers. This study aimed to functionally characterize an enhancer ∼55 kb… read more here.
Keywords: expression; tnfaip3; risk; enhancer upstream ... See more keywords