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   Articles with "uptake nanoparticles" as a keyword



Penetration and Uptake of Nanoparticles in 3D Tumor Spheroids.

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recommendations! Published in 2019 at "Bioconjugate chemistry"

DOI: 10.1021/acs.bioconjchem.9b00136

Abstract: Animal models are effective for assessing tumor localization of nanosystems but difficult to use for studying penetration beyond the vasculature. Here, we have used well-characterized HCT116 colorectal cancer spheroids to study the effect of nanoparticle… read more here.

Keywords: poly styrene; penetration; nanoparticles tumor; styrene nanoparticles ... See more keywords

Uncovering the Importance of Ligand Mobility on Cellular Uptake of Nanoparticles: Insights from Experimental, Computational, and Theoretical Investigations.

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recommendations! Published in 2024 at "ACS nano"

DOI: 10.1021/acsnano.3c11982

Abstract: The cellular uptake of nanoparticles (NPs) by biological cells is an important and fundamental process in drug delivery. Previous studies reveal that the physicochemical properties of nanoparticles as well as those of functionalized ligands can… read more here.

Keywords: cellular uptake; conjugation strategy; ligand mobility; uptake nanoparticles ... See more keywords
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Cellular uptake of nanoparticles: journey inside the cell.

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recommendations! Published in 2017 at "Chemical Society reviews"

DOI: 10.1039/c6cs00636a

Abstract: Nanoscale materials are increasingly found in consumer goods, electronics, and pharmaceuticals. While these particles interact with the body in myriad ways, their beneficial and/or deleterious effects ultimately arise from interactions at the cellular and subcellular… read more here.

Keywords: nanoparticles journey; inside cell; journey inside; uptake nanoparticles ... See more keywords

Can dual-ligand targeting enhance cellular uptake of nanoparticles?

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recommendations! Published in 2017 at "Nanoscale"

DOI: 10.1039/c7nr01020f

Abstract: Dual ligand targeting to different types of over-expressed receptors on cell surfaces is a promising strategy in nanomedicine. Here, by using dissipative particle dynamics simulations, the effect of the surface distribution and physicochemical properties of… read more here.

Keywords: ligand targeting; dual ligand; uptake nanoparticles; dual ligands ... See more keywords