Penetration and Uptake of Nanoparticles in 3D Tumor Spheroids.
Sign Up to like & getrecommendations! Published in 2019 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.9b00136
Abstract: Animal models are effective for assessing tumor localization of nanosystems but difficult to use for studying penetration beyond the vasculature. Here, we have used well-characterized HCT116 colorectal cancer spheroids to study the effect of nanoparticle… read more here.
Keywords: poly styrene; penetration; nanoparticles tumor; styrene nanoparticles ... See more keywords
Cellular uptake of nanoparticles: journey inside the cell.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical Society reviews"
DOI: 10.1039/c6cs00636a
Abstract: Nanoscale materials are increasingly found in consumer goods, electronics, and pharmaceuticals. While these particles interact with the body in myriad ways, their beneficial and/or deleterious effects ultimately arise from interactions at the cellular and subcellular… read more here.
Keywords: nanoparticles journey; inside cell; journey inside; uptake nanoparticles ... See more keywords
Can dual-ligand targeting enhance cellular uptake of nanoparticles?
Sign Up to like & getrecommendations! Published in 2017 at "Nanoscale"
DOI: 10.1039/c7nr01020f
Abstract: Dual ligand targeting to different types of over-expressed receptors on cell surfaces is a promising strategy in nanomedicine. Here, by using dissipative particle dynamics simulations, the effect of the surface distribution and physicochemical properties of… read more here.
Keywords: ligand targeting; dual ligand; uptake nanoparticles; dual ligands ... See more keywords