ER-mitochondria distance is a critical parameter for efficient mitochondrial Ca2+ uptake and oxidative metabolism
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DOI: 10.1038/s42003-024-06933-9
Abstract: IP3 receptor (IP3R)-mediated Ca2+ transfer at the mitochondria-endoplasmic reticulum (ER) contact sites (MERCS) drives mitochondrial Ca2+ uptake and oxidative metabolism and is linked to different pathologies, including Parkinson’s disease (PD). The dependence of Ca2+ transfer… read more here.
Keywords: mitochondrial ca2; oxidative metabolism; uptake oxidative; ca2 ... See more keywords