Cellular uptake properties of lamotrigine in human placental cell lines: Investigation of involvement of organic cation transporters (SLC22A1-5).
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DOI: 10.1016/j.dmpk.2020.01.005
Abstract: Lamotrigine (LTG) is an important antiepileptic drug for the treatment of seizures in pregnant women with epilepsy. However, it is not known if the transport of LTG into placental cells occurs via a carrier-mediated pathway.… read more here.
Keywords: cell lines; organic cation; uptake properties; placental cell ... See more keywords