Tandem lesions arising from 5-(uracilyl)methyl peroxyl radical addition to guanine: Product analysis and mechanistic studies.
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DOI: 10.1021/acs.chemrestox.9b00407
Abstract: The reaction of hydroxyl radical (HO●) with thymine in DNA generates 5-(uracilyl)-methyl radicals (T●) and the corresponding methylperoxyl radical (TOO●) in the presence of O2, which in turn propagates damage by reacting with a vicinal… read more here.
Keywords: tandem lesions; guanine; uracilyl methyl; addition guanine ... See more keywords