Articles with "urat1 inhibitors" as a keyword



Discovery and characterization of verinurad, a potent and specific inhibitor of URAT1 for the treatment of hyperuricemia and gout

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Published in 2017 at "Scientific Reports"

DOI: 10.1038/s41598-017-00706-7

Abstract: Gout is caused by elevated serum urate levels, which can be treated using inhibitors of the uric acid transporter, URAT1. Here, we characterize verinurad (RDEA3170), which is currently under evaluation for gout therapy. Verinurad specifically… read more here.

Keywords: uric acid; urat1 inhibitors; verinurad; characterization verinurad ... See more keywords