Down-regulation of ABCG2, a urate exporter, by parathyroid hormone enhances urate accumulation in secondary hyperparathyroidism.
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DOI: 10.1016/j.kint.2016.09.041
Abstract: Hyperuricemia occurs with increasing frequency among patients with hyperparathyroidism. However, the molecular mechanism by which the serum parathyroid hormone (PTH) affects serum urate levels remains unknown. This was studied in uremic rats with secondary hyperparathyroidism… read more here.
Keywords: pth; parathyroid hormone; urate exporter; expression ... See more keywords