The Impact of Urate-Lowering Therapy in Post-Myocardial Infarction Patients: Insights from a Population-Based, Propensity Score-Matched Analysis.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical pharmacology and therapeutics"
DOI: 10.1002/cpt.2473
Abstract: The role of urate-lowering therapy (ULT) for the primary prevention of cardiovascular events has been widely discussed, but its evidence for the secondary prevention of myocardial infarction (MI) is limited. Therefore, we conduct a population-based,… read more here.
Keywords: ult; propensity score; post; urate lowering ... See more keywords
Cardiovascular Disease in Gout and the Protective Effect of Treatments Including Urate-Lowering Therapy
Sign Up to like & getrecommendations! Published in 2019 at "Drugs"
DOI: 10.1007/s40265-019-01081-5
Abstract: Cardiovascular disease affects more than 90 million Americans. Recent studies support an increased cardiovascular disease risk in inflammatory conditions, such as gout. Increased serum urate levels, or hyperuricemia, are a precursor to gout. Data from… read more here.
Keywords: lowering therapy; gout; disease; urate lowering ... See more keywords
Temporal evolution of urate crystal deposition over articular cartilage after successful urate-lowering therapy in patients with gout: An ultrasonographic perspective
Sign Up to like & getrecommendations! Published in 2017 at "Modern Rheumatology"
DOI: 10.1080/14397595.2016.1214229
Abstract: Abstract Objective: To detect evolution of ultrasonographic signs of deposition of monosodium urate crystals (MSUC) in gouty joints by serial ultrasonography after initiation of urate-lowering therapy (ULT). Methods: Adult gout patients were examined by serial… read more here.
Keywords: dcs; lowering therapy; deposition; urate lowering ... See more keywords
Safety and tolerability of available urate-lowering drugs: a critical review
Sign Up to like & getrecommendations! Published in 2019 at "Expert Opinion on Drug Safety"
DOI: 10.1080/14740338.2019.1594771
Abstract: ABSTRACT Introduction: Urate-lowering therapy (ULT) is the cornerstone of gout management, which is a widespread chronic illness characterized by hyperuricemia, arthropathy, tophus development, and urolithiasis. Since asymptomatic increased serum urate levels are associated with a… read more here.
Keywords: safety tolerability; safety; lowering drugs; urate lowering ... See more keywords
Update on gout management: what is old and what is new.
Sign Up to like & getrecommendations! Published in 2021 at "Current opinion in rheumatology"
DOI: 10.1097/bor.0000000000000861
Abstract: PURPOSE OF REVIEW The global burden of gout is rising, as are the prevalence of associated comorbidities, all-cause mortality and societal costs. In this review, we discuss recent advances in epidemiology and treatment strategies for… read more here.
Keywords: gout management; management; gout; risk ... See more keywords
Comparative Safety of Gout Treatment Strategies on Cardiovascular Outcomes Using Observational Data: Clone-censor-weight Target Trial Emulation Approach
Sign Up to like & getrecommendations! Published in 2023 at "Epidemiology"
DOI: 10.1097/ede.0000000000001608
Abstract: Background: We sought to examine the cardiovascular safety of intensive treat-to-target serum urate strategies for gout using Medicare claims data linked to electronic health record laboratory data. Methods: We selected patients with gout who initiated… read more here.
Keywords: safety; lowering therapy; urate lowering; target ... See more keywords
Urate‐lowering therapy for patients with gout on hemodialysis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Rheumatic Diseases"
DOI: 10.1111/1756-185x.14334
Abstract: Gout is the most common form of inflammatory arthritis and is caused by deposition of monosodium urate crystals resulting from a high burden of uric acid (UA). High UA burden also has been associated with… read more here.
Keywords: therapy patients; patients gout; gout hemodialysis; lowering therapy ... See more keywords
Cardiovascular risk of urate‐lowering drugs: A study using the National Database of Health Insurance Claims and Specific Health Checkups of Japan
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Translational Science"
DOI: 10.1111/cts.13439
Abstract: In the present study, we aimed to investigate the association between urate‐lowering drugs and cardiovascular events, primarily focusing on the risk of febuxostat and topiroxostat when compared with allopurinol in Japan. We conducted an observational… read more here.
Keywords: health; lowering drugs; group; urate lowering ... See more keywords
Efficacy and safety of urate‐lowering treatments in patients with hyperuricemia: A comprehensive network meta‐analysis of randomized controlled trials
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Pharmacy and Therapeutics"
DOI: 10.1111/jcpt.13156
Abstract: Hyperuricemia (HUA) and gout are considerable public health problems because of their increasing incidence and interactions with other diseases. We aimed to evaluate the efficacy and safety of urate‐lowering therapies (ULTs) for patients. read more here.
Keywords: efficacy safety; lowering treatments; safety urate; urate lowering ... See more keywords
OP0051 DEVELOPMENT OF A MULTIVARIABLE IMPROVEMENT MEASURE FOR GOUT
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2019-eular.2904
Abstract: Background Inflammatory rheumatic diseases are generally multifaceted disorders and the complex pathology underlying these conditions makes it difficult to assess patient status and the efficacy of therapy with a single outcome measure. This has prompted… read more here.
Keywords: gout; multivariable improvement; measure; urate lowering ... See more keywords
AB0865 GOUT IN HOSPITALISED PATIENTS FOR CARDIOVASCULAR DISEASES: PREVALENCE AND MANAGEMENT STATUS
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2019-eular.3651
Abstract: Background Gout is an independent risk factor for cardiovascular diseases (CVDs), where the urate crystal-led inflammatory state likely has a key role. Crystal dissolution may carry with cardiovascular benefits, so optimal management of gout patients… read more here.
Keywords: serum urate; prevalence; cardiovascular diseases; management ... See more keywords