Urate Oxidase produced by Lucilia sericata medical maggots is localized in Malpighian tubes and facilitates allantoin production.
Sign Up to like & getrecommendations! Published in 2017 at "Insect biochemistry and molecular biology"
DOI: 10.1016/j.ibmb.2017.02.007
Abstract: Lucilia sericata maggots are the only species currently approved for maggot debridement therapy (MDT), an alternative treatment for chronic and recalcitrant wounds. Maggots promote wound debridement, disinfection and healing by producing a complex mixture of… read more here.
Keywords: production; malpighian tubes; sericata; lucilia sericata ... See more keywords
Engineered Escherichia coli Nissle 1917 with urate oxidase and an oxygen-recycling system for hyperuricemia treatment
Sign Up to like & getrecommendations! Published in 2022 at "Gut Microbes"
DOI: 10.1080/19490976.2022.2070391
Abstract: ABSTRACT Hyperuricemia is the second most prevalent metabolic disease to human health after diabetes. Only a few clinical drugs are available, and most of them have serious side effects. The human body does not have… read more here.
Keywords: coli nissle; escherichia coli; engineered escherichia; urate oxidase ... See more keywords
Enhancement of Pharmaceutical Urate Oxidase Thermostability by Rational Design of De Novo Disulfide Bridge
Sign Up to like & getrecommendations! Published in 2020 at "Iranian Journal of Biotechnology"
DOI: 10.30498/ijb.2020.2662
Abstract: Background and Purpose: As a therapeutic enzyme, urate oxidase is utilized in the reduction of uric acid in various conditions such as gout or tumor syndrome lysis. However, even bearing kinetical advantage over other counterparts,… read more here.
Keywords: novo disulfide; rational design; oxidase; disulfide bridge ... See more keywords
Urate oxidase from tea microbe Colletotrichum camelliae is involved in the caffeine metabolism pathway and plays a role in fungal virulence
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2022.1038806
Abstract: Tea is one of the most well-known, healthy beverages in the world. Tea plants produce caffeine as a secondary metabolite. Colletotrichum camelliae is one of the most important microbes frequently isolated from tea fields, and… read more here.
Keywords: caffeine metabolism; fungal virulence; tea; urate oxidase ... See more keywords