Conformation and Visual Distinction between Urea and Thiourea Derivatives by an Acetate Ion and a Hexafluorosilicate Cocrystal of the Urea Derivative in the Detection of Water in Dimethylsulfoxide
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DOI: 10.1021/acsomega.7b01217
Abstract: Structures of different solvates and solute–solvent interactions of 4-(3-(4-nitrophenyl)urido)benzoate (L1) and methyl-4-(3-(4-nitrophenyl)thiourido)benzoate (L2) with different solvents are analyzed. The solution of L1 with tetrabutylammonium acetate (TBAA) in dimethylsulfoxide (DMSO) is colorless, but a similar solution… read more here.
Keywords: self assembly; thiourea derivatives; water; urea derivative ... See more keywords
A novel approach to white-light emission using a single fluorescent urea derivative and fluoride
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DOI: 10.1039/c8nj05105d
Abstract: First observation of white fluorescence using a single fluorescent urea derivative and fluoride. read more here.
Keywords: fluorescent urea; derivative fluoride; urea derivative; novel approach ... See more keywords
Novel urea derivative-loaded PLGA nanoparticles to inhibit caries-associated Streptococcus mutans
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DOI: 10.1039/d1ra09314b
Abstract: Caries is the most common chronic infectious disease in the human oral cavity and the existing anti-caries agents may lead to drug resistance and microecological imbalance. A novel urea derivative, 1,3-bis[3,5-bis(trifluoromethyl)phenyl]urea, has a potentially prominent… read more here.
Keywords: loaded plga; urea derivative; novel urea; streptococcus mutans ... See more keywords
Diaryl Urea Derivative Molecule Inhibits Cariogenic Streptococcus mutans by Affecting Exopolysaccharide Synthesis, Stress Response, and Nitrogen Metabolism
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.904488
Abstract: Different small molecules have been developed to target cariogenic bacteria Streptococcus mutans. Based on target-based designing and in silico screening, a novel diaryl urea derivative, 1,3-bis[3,5-bis(trifluoromethyl)phenyl]urea (BPU), has previously been found effective in inhibiting the… read more here.
Keywords: urea derivative; stress response; streptococcus mutans; molecule ... See more keywords
Targeting USP-7 by a Novel Fluorinated 5-Pyrazolyl-Urea Derivative
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24119200
Abstract: The impact of innovative technologies on the target discovery has been employed here to characterize the interactome of STIRUR 41, a promising 3-fluoro-phenyl-5-pyrazolyl-urea derivative endowed with anti-cancer activity, on neuroblastoma-related cells. A drug affinity responsive… read more here.
Keywords: urea derivative; pyrazolyl urea; fluorinated pyrazolyl; targeting usp ... See more keywords